Tom and Jerry: Blast Off to Mars is a DVD outer-space-themed direct-to-video film. It was released on DVD and VHS on January 18, 2005, and on Blu-ray on October 16, 2012.
Tom and Jerry accidentally have a chase leading them onto a spaceship which Buzz Blister and Biff Buzzard are taking to Mars. Then Tom and Jerry run off again once on Mars. Then they encounter Martians that mistake Jerry for someone from a prophecy and treat him well. But Tom accidentally destroys their city and is about to be dumped into lava. But a Martian saves Tom and Jerry, Jerry and the Martian escape to Earth. But Martians disintegrated some people after Buzz said there was no life on Mars. But the friendly Martian saves the disintegrated people, but Martians attack with a giant machine. But there's Spike, who will do anything to enjoy his bone. Tom throws it into the Martian machine, and Spike destroys the machine (and gets his bone back) when a party is held for Tom and Jerry, Spike repairs the machine and Tom gets chased while the others have a happy ending.
|Charlie Schlatter||Jerry Mouse|
|Dee Bradley Baker||Tom Cat|
|Kathryn Fiore||Peep / Press Girl|
|Corey Burton||Martian Scientist / Court Attendant / Eyes at Gate|
|Jeff Glen Bennett||Dr. Gluckman / Martian Guard #1 / President|
|Brad Garrett||Commander Bristle / Martian Guard #3|
|Jess Harnell||Major Buzz Blister / Martian General / Worker #3|
|Tom Kenny||Grob / Gardener #1 / Martian Guard #2|
|Rob Paulsen||Computer Voice / Worker #1 / Worker #2|
|Bill Kopp||Press Guy|
|Frank Welker||Spike Bulldog|
|Billy West||Major Biff Buzzard / King Thingg / Gardener #2|
- In Tom and Jerry: Blast Off to Mars, a poster of Tom and Jerry: Blast Off to Mars can be seen when Tom and Jerry are racing in the final race.
- Main article: Tom and Jerry: Blast Off to Mars/Gallery