Screwball "Screwy" Squirrel is a cartoon character, an anthropomorphic squirrel created by Tex Avery for Metro-Goldwyn-Mayer, generally considered the wackiest of the screwball cartoon characters of the 1940s.

Both Screwy Squirrel and his archnemesis, Meathead make appearances as residents of 'Fairyland' in Tom and Jerry's Giant Adventure retaining most of their traits. Screwy Squirrel is now voiced by Paul Reubens and Meathead is voiced by John DiMaggio.

Screwy Squirrel made a silent cameo appearance in The Tom & Jerry Show (2014 seies) episode, "Kid Stuff".